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For the intestinal wellbeing. 

  • Innovative solution for Irritable Bowel Syndrome (IBS)
  • Modulation of the gut microbiota
  • Clinically Tested
  • Patented

BIOintestil®, an innovative formulation based on palmarosa essential oil and ginger powder, is a patented ingredient for Irritable Bowel Syndrome (IBS) and modulation of the gut microbiota.

BIOintestil® is an innovative natural ingredient for dietary supplements with eubiotic activity, created with a patented formulation based on Palmarosa essential oil (Cymbopogon martinii), adsorbed onto ginger rhizome powder (Zingiber officinale). Based on preclinical studies and two clinical trials conducted on patients with Irritable Bowel Syndrome (IBS) at the Department of Medical and Surgical Sciences of the University of Bologna and the Department of Clinical and Experimental Sciences at the Spedali Civili of Brescia, in Italy, BIOintestil® has shown to positively modulate the gut microbiota, reduce abdominal bloating, regulate bowel movements, and normalize intestinal functions.

BIOintestil® is indicated for the formulation of dietary supplements to support digestive function alterations, such as abdominal pain and bloating, irregular bowel movements, diarrhea, constipation, flatulence, indigestion, nausea, and vomiting, symptoms typical of Irritable Bowel Syndrome (IBS). You can find it in BIOintestil Complex.

In the innovative formulation of BIOintestil®, the palmarosa oil adsorbed onto ginger powder is able to pass intact through the stomach and the first part of the intestine. The bioavailability of geraniol, the main component of palmarosa essential oil, in this formulation is 16%, whereas in its free form, it is 92%, as confirmed by our pharmacokinetic studies. The digestion of ginger fiber by the gut microbiota exerts a prebiotic effect and allows the release of essential oil directly into the colon, where it can exert its anti-inflammatory and antimicrobial effect, improving the composition of the gut microbiota and intestinal mucosal functionality.

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BIOintestil® is an innovative natural ingredient for the formulation of food supplements. It contains essential oil of Palmarosa (Cymbopogon martinii) and powder of Ginger rhizome (Zingiber officinale Roscoe.) offer valuable support for digestive functions.

Eubiotics are positive modulators of the gut microbiota that do not belong to the category of probiotics, prebiotics or postbiotics. The term refers to various natural substances such as certain essential oils that can positively modify the gut microbiota. The general term ‘eubiotic’ is related to the Greek term ‘eubiosis’ and refers to an optimal balance of the microbiota in the gastrointestinal tract. The main purpose of using a product with eubiotic action is to maintain or restore intestinal eubiosis.

BIOintestil® is an innovative eubiotic food supplement. The product provides valuable support in the management of disorders associated with IBS, but it does not work in the same way as probiotics or prebiotics. It cannot be considered a probiotic, nor does it help other microorganisms to grow, so it cannot be considered a prebiotic. It is not an antibiotic (it cannot kill all micro-organisms in general, nor pathogens such as Salmonella) but acts selectively by counteracting the growth of only ‘opportunistic pathogens’. These are bacteria commonly found in the gut, which can cause dysbiosis and even disease when they grow above a certain number and at the expense of other gut bacteria. Therefore, a eubiotic such as BIOintestil® helps to maintain the right levels of opportunistic pathogens without affecting commensal bacteria and can help to make the environment conducive to rebalancing the microbiota by also regulating digestive function.

Thanks to the properties of Palmarosa oil, which promotes digestive function, relaxation, and mental well-being, and ginger, which aids digestion, regular gastrointestinal motility, the elimination of gas, and counters localized tension in the intestines, BIOintestil® is a powerful synergy that supports gastrointestinal well-being.

In the innovative formulation of BIOintestil®, the use of ginger rhizome powder in the blend allows Palmarosa oil to remain adsorbed in the fiber and pass intact through the first part of the intestine. Thanks to this, the Palmarosa oil is mainly released in the colon. This particular formulation and the richness of fibers promote natural balance of the intestinal flora.

Based on preclinical scientific studies and two clinical trials on patients suffering from IBS, conducted at the Department of Medical and Surgical Sciences of the S. Orsola Hospital of the University of Bologna and the Department of Clinical and Experimental Sciences of the Spedali Civili Hospital in Brescia, BIOintestil® has been shown to positively modulate the intestinal microbiota, reduce abdominal bloating and to optimise the intestinal function of these patients. These data were obtained in a double-blind placebo-controlled clinical study.

-Cymbopogon Martinii essential oil and Zingiber officinale Roscoe rhizome powder are certified for food grade use.
-According to DM 27/03/2014 of the Italian Ministry of Health, the use of Cymbopogon martinii essential oil is approved in food supplements for digestive function.
-According to DM 27/03/2014 of the Italian Ministry of Health, the use of Zingiber officinale is approved in food supplements for digestive function, regulation of gastrointestinal motility and gas elimination.
-According to Regulation 15/2283 of the European Parliament and of the Council of 25 November 2015 on Novel Food, BIOintestil® does not meet the definition of “Novel Food”.
According to Regulation (EC) 1924/2006 of the European Parliament and of the Council of 20 December 2006 on nutrition and health claims made on foods, BIOintestil® can be defined as a “source of fibre”.
-According to Regulation (EC) 1907/2006, BIOintestil® is composed of 100% natural ingredients that meet the definition of “naturally occurring substances.

The basic ingredients of BIOintestil® – Palmarosa and Ginger – naturally do not contain Gluten. However, the production chain is not certified Gluten Free, so BIOintestil® may have traces of Gluten from the manufacturing process.

BIOintestil® is GMO-free. It does not contain, derive from or consist of Genetically Modified Organisms. BIOintestil® complies with EC Regulations 1829/2003 and 1830/2003. In particular:

Regulation (EC) No 1829/2003 of the European Parliament and of the Council of 22 September 2003 on genetically modified food and feed and
Regulation (EC) No 1830/2003 of the European Parliament and of the Council of 22 September 2003 on the traceability and labelling of genetically modified organisms and the traceability of food and feed products produced from genetically modified organisms.

The formulation of BIOintestil® and its production technology are patented (European Patent EP- 3097921).

Each ingredient in BIOintestil® comes from China/India (Ginger) and Brazil (Palmrose), their native lands, while their processing takes place in Italy – e.g. Ginger is dried and powdered in Italy.
The quality of the raw materials is double-checked: Ginger and Palmarosa arrive in Italy with their own analysis certifications. Distributors verify these certifications while conducting their own quality control and quality assurance procedures. The raw materials are also subsequently checked in the final product

TGD s.r.l. checks the raw materials and the final product with its own analyses. These analyses include, for example, tests for the presence of pesticides, pollutants, mycotoxins, allergens, pathogenic bacteria such as salmonella and coliforms, and much more.

– Fresh Ginger is dried and processed into powder in Italy.
– Palmrose Essential Oil is added to the mixture and adsorbed into the powder in Italy.

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