Pain refers to an unpleasant sensory and emotional experience associated with actual or potential tissue damage. Acute pain is characterized by a physiological response to a harmful stimulus and typically lasts for less than four weeks. However, if the duration of the painful sensation exceeds this timeframe, it is referred to as subacute or chronic pain. In the majority of cases, chronic pain is related to the presence of low-grade inflammatory processes underlying a disease that is its main source. Chronic pain can affect various regions, with the most commonly reported being joints (including knees), back, head (migraine), abdominal, and genital pain. In some cases, it may emerge following pharmacological treatments or surgical interventions. Currently, available therapies for pain management include nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids, both of which are effective but their chronic use is associated with significant side effects.
Supplement